Bacterial persistence increases as environmental fitness decreases
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چکیده
منابع مشابه
Bacterial persistence increases as environmental fitness decreases
Since persister cells cause chronic infections and since Escherichia coli toxin MqsR increases persisters, we used protein engineering to increase the toxicity of MqsR to gain insights into persister cell formation. Through two amino acid replacements that increased the stability of MqsR, toxicity and persistence were increased. A whole-transcriptome study revealed that the MqsR variant increas...
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ژورنال
عنوان ژورنال: Microbial Biotechnology
سال: 2012
ISSN: 1751-7915,1751-7915
DOI: 10.1111/j.1751-7915.2011.00327.x